Live blogging a lab meeting

So I thought I'd give a few people an idea of what I do every Thursday. I decided to live blog a lab meeting.

8:35 - We arrive in room, there are a noticeable amount of seats missing
8:37 - Projector turns on, we wait
8:39 - Brian introduces the topic, DMT1
8:40 - Figure #2 comes up first, he explains that the order is to help us understand, not necessarily exactly how they were published
8:41 - DMT1 seems to control Cu (I) and Fe (II) transport
8:42 - Figure #3. Ascorbate controls the uptake of Cu AND Fe (III)
8:43 - The "more important" figures - figure #4 - As you treat with more Fe you actually decrease the amount of Fe being taken up over 60 mins, same thing with Cu
8:44 - "The money shot." Using Antisense to DMT1, to decrease DMT1 presence, you get a decrease in not only Fe, but also in Cu.
8:45 - Brian pines for a marker (oops, I forgot to grab those). He starts to explain that DMT1 may be another player in not only Cu but also in moving DDP (we know there are other transporters b/c CTR1 -/- still move DDP). Seems that DMT1 is expressed on the cell surface and also in the exosomes.
8:46 - There may be competition between CTR2 and DMT1 in the fight to accumulate DDP and Cu. First plan of attack is to run and SRB or two to get a baseline to see if there is increased accumulation. Then maybe do some uptake studies.
8:47 - That's it! Wow that was SHORT! Nice job, Brian.


**Note this happened on the 17th of June- I just finally got it posted.